Pharmacogenetic Testing

Everyone has unique, complex genetic characteristics. We typically think of these as things that determine our eye color or whether we are likely to develop certain diseases and disorders. However, genetics also affect how we respond to most commonly prescribed medications.

More than 75% of people have genetic variations that determine how their bodies process and use drugs. This applies not only to prescription medications, but also to over-the-counter medicines, herbal and dietary supplements, and recreational drugs such as marijuana.

Because of these genetic differences, two people can take the same dose of the same drug, but respond in very different ways. For example, the drug might work very well for one person, but not at all for another. Or the drug might cause side effects for one person, but not for someone else.

In some cases, drug-related side effects can be serious or cause death – even though the drug was prescribed correctly by the doctor and used correctly by the patient. People who take several different drugs face an even greater risk of dangerous side effects, especially if they are over 65 years of age.

Each year, millions of people are hospitalized because of dangerous side effects caused by drugs. In fact, serious drug-related effects are the 4th leading cause of death in the US.

Pharmacogenetic Testing is a non-invasive genetic test utilizing either a buccal or saliva specimen to identify how a patient’s genetic profile may impact his or her response to certain medications. Two patients, with the same diagnosis and prescribed the same medication and dose, may exhibit significantly different clinical responses.

The information from the test may help clinicians make more effective prescribing decisions that are personalized for each patient

Benefits of Pharmacogenetic Testing:

• Improve the effectiveness of the medications you take;
• Reduce negative side effects;
• Prevent serious drug reactions; and
• Avoid buying and using drugs that won’t work for you.